Osteoimmunopathology

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Osteoimmunopathology


Osteoimmunopathology
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Osteoimmunopathology


Osteoimmunopathology
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Author : Francesco Chiappelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-30

Osteoimmunopathology written by Francesco Chiappelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-30 with Medical categories.


Osteoimmunology pertains to the study of the relationship between the bones, particularly the bone marrow, and the immune system. This monograph pursues the best available evidence, by means of research synthesis, for the characterization of the physiological relevance and pathological implications of the inter-connectedness between the skeletal and the immune system. Research will be discussed that highlights the associated role of the circulatory, nervous and endocrine systems, as well as proteomic and genomic pathways and signatures. Emphasis is given that domain of medicine that relates to the oral cavity, its diseases and their systemic sequelae. This monograph arises from observations that have suggested that the skeletal system and the immune system are intimately intertwined. Chronic inflammatory reactions subsequent to an excessive immune reaction can damage the bones, as in rheumatoid arthritis (RA), osteoporosis, patients seropositive for the human immunodeficiency virus (HIV)-1 and with signs and symptoms of the acquired immune deficiency syndrome (AIDS), and bone cancer. Bones – in particular the bone marrow – are one of the primary locations in which cells of the immune system mature. In brief, this monograph begins to answer a range of questions, such as, what is osteoimmunology all about?, does the immune system and its components affect bone development?, how do stress hormones impact upon the pathophysiology of bone-immune interactions?, can the scientific process of research synthesis, obtain the best available evidence for treatment of diseases involving the bone-immune entity (i.e., osteo immunopathologies) means of evidence-based clinical decision-making directed at the treatment of osteoimmune pathologies?

Temporomandibular Joint And Airway Disorders


Temporomandibular Joint And Airway Disorders
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Author : G. Gary Demerjian
language : en
Publisher: Springer
Release Date : 2018-11-03

Temporomandibular Joint And Airway Disorders written by G. Gary Demerjian and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-03 with Medical categories.


This book on the local and systemic manifestations and correlates of temporomandibular joint disorders (TMDs) encompasses the two intertwined facets of translational science – translational research and translational effectiveness – as they relate specifically to TMDs. The first part of the book, on recent translational research, focuses on topics such as the neuroanatomy and neurophysiology of the trigeminal nerve and trigeminal network system, the manifestations of neuroinflammation in TMDs, and the molecular mechanisms underlying TMDs. The second part discusses the clinical effectiveness of treatment approaches from the perspective of evidence-based dentistry, with careful attention to the critical relationships between dental malocclusions, the signs and symptoms of TMDs, and airway/breathing disorders. Interventions to correct for malocclusal conditions that lead to TMDs are examined, with explanation of the ways in which they can ameliorate a variety of local and systemic symptoms. This will be an excellent reference book for established practitioners, residents, interns, and students as well as a powerful cutting-edge document for researchers in the field.

Fundamentals Of Evidence Based Health Care And Translational Science


Fundamentals Of Evidence Based Health Care And Translational Science
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Author : Francesco Chiappelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-18

Fundamentals Of Evidence Based Health Care And Translational Science written by Francesco Chiappelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-18 with Medical categories.


Comparative effectiveness research – the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options – is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing “complex” systematic reviews, “cumulative” meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.

Hiv And Endocrine Disorders An Issue Of Endocrinology And Metabolism Clinics Of North America


Hiv And Endocrine Disorders An Issue Of Endocrinology And Metabolism Clinics Of North America
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Author : Paul Hruz
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-08-17

Hiv And Endocrine Disorders An Issue Of Endocrinology And Metabolism Clinics Of North America written by Paul Hruz and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-17 with Medical categories.


This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Paul Hruz, is devoted to HIV and Endocrine Disorders. Articles in this issue include: Dyslipidemia and cardiovascular risk in HIV infection; Changes in nutritional concerns in HIV/AIDS; HIV Lipodystrophy: Lessons learned about adipose tissue and metabolic disorders; Hypogonadism in the HIV infected male; Gonadal function and reproductive health in women with HIV; Osteopenia, osteoporosis, and fracture risk with HIV infection and treatment; HIV-associated calcium and vitamin D abnormalities; Alterations in pancreatic islet function in HIV; Insulin resistance, glucose intolerance, and diabetes in HIV; Thyroid abnormalities in HIV; HPA axis/adrenal pathology in HIV; and Endocrinopathies in HIV-infected children.

Contemporary Topics About Phosphorus In Biology And Materials


Contemporary Topics About Phosphorus In Biology And Materials
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Author : David Churchill
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-09-09

Contemporary Topics About Phosphorus In Biology And Materials written by David Churchill and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-09 with Technology & Engineering categories.


This book addresses a diverse set of topics regarding phosphorus chemistry, namely phosphates and closely related chemical systems. Divided into two sections, chapters cover such topics as phosphate dynamics and phosphates in biomaterials. This volume is a useful reference for scholars and researchers and will inspire readers to make future discoveries in the field.

Global Virology Iii Virology In The 21st Century


Global Virology Iii Virology In The 21st Century
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Author : Paul Shapshak
language : en
Publisher: Springer Nature
Release Date : 2019-11-22

Global Virology Iii Virology In The 21st Century written by Paul Shapshak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-22 with Medical categories.


Global Virology, Volume III: Virology in the 21st Century examines work that has been undertaken, or is planned, in several fields of virology, in an effort to promote current and future work, research, and health. Fields and methods addressed include virology, immunology, space research, astrovirology/astrobiology, plasmids, swarm intelligence, bioinformatics, data-mining, machine learning, neural networks, critical equations, and advances in biohazard biocontainment. Novel and forward-looking methods, techniques, and approaches in research and development are presented by experts in the field.

Musculoskeletal Medicine In Primary Care


Musculoskeletal Medicine In Primary Care
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Author : Dr Solomon Abrahams PhD MSc BSc MCSP
language : en
Publisher: Xlibris Corporation
Release Date : 2014-02-18

Musculoskeletal Medicine In Primary Care written by Dr Solomon Abrahams PhD MSc BSc MCSP and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-18 with Medical categories.


This book is designed to help MSK Physicians, Physiotherapists, Osteopaths, G.Ps and other respected colleagues in the examination, diagnosis and management of Common MSK pathologies presenting in primary care. Chapters are sectioned according to the anatomical area of the body. Each chapter consists of Basic Anatomy, Subjective (including differential diagnosis and red flags) and Objective examination, Observation and Physical examination, special tests (and their reliability), Pathologies, key points and flow charts for triaging. Where possible, we have used evidence based research to suppliment the practice based experience within the book. Some special chapters are dedicated to common pathologies seen in the elderly and children/ adolescents. Other chapters include Joint injections in primary care, Medicines that conflict with MSK diagnosis/management, common blood results and their meaning and common connective tissue disorders. Where possible, we have supplemented chapters with Scans, X rays, Pictures and flow charts to help explain the simplicity of each pathology. The flow charts at the end of each primary chapter is to help triage pathologies.