Neuroprogression In Psychiatry

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Neuroprogression In Psychiatry


Neuroprogression In Psychiatry
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Neuroprogression In Psychiatric Disorders


Neuroprogression In Psychiatric Disorders
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Author : A. Halaris
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-07-25

Neuroprogression In Psychiatric Disorders written by A. Halaris and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-25 with Medical categories.


In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field.

Neuroprogression In Psychiatry


Neuroprogression In Psychiatry
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Author : Flávio Kapczinski
language : en
Publisher: Oxford University Press
Release Date : 2019-03-06

Neuroprogression In Psychiatry written by Flávio Kapczinski and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-06 with Medical categories.


Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.

Neuroprogression And Staging In Bipolar Disorder


Neuroprogression And Staging In Bipolar Disorder
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Author : Flávio Kapczinski
language : en
Publisher: Oxford University Press, USA
Release Date : 2015

Neuroprogression And Staging In Bipolar Disorder written by Flávio Kapczinski and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.


Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--

Inflammation And Immunity In Depression


Inflammation And Immunity In Depression
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Author : Bernhard Baune
language : en
Publisher: Academic Press
Release Date : 2018-05-23

Inflammation And Immunity In Depression written by Bernhard Baune and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-23 with Medical categories.


Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

Bipolar Disorder Vulnerability


Bipolar Disorder Vulnerability
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Author : Jair Soares
language : en
Publisher: Academic Press
Release Date : 2018-06-09

Bipolar Disorder Vulnerability written by Jair Soares and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-09 with Medical categories.


Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness. Highlights diverse translational methodologies, including functional and structural neuroimaging, neuropsychological testing and integrated genomics Examines molecular trajectories in youth with bipolar disorder and unaffected youth at high risk for developing bipolar disorder Explores the interaction between genomic and environmental influences that shape behavior

Clinical Staging In Psychiatry


Clinical Staging In Psychiatry
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Author : Patrick D. McGorry
language : en
Publisher: Cambridge University Press
Release Date : 2019-07-31

Clinical Staging In Psychiatry written by Patrick D. McGorry and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-31 with Medical categories.


Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.

The Schizophrenia Spectrum


The Schizophrenia Spectrum
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Author : Spaulding, William D.
language : en
Publisher: Hogrefe Publishing
Release Date : 2017-01-31

The Schizophrenia Spectrum written by Spaulding, William D. and has been published by Hogrefe Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-31 with Psychology categories.


The new edition of this highly acclaimed volume provides a fully updated and comprehensive account of the psychopathology, clinical assessment, and treatment of schizophrenia spectrum disorders. It emphasizes functional assessment and modern psychological treatment and rehabilitation methods, which continue to be under-used despite overwhelming evidence that they improve outcomes. The compact and easy-to-read text provides both experienced practitioners and students with an evidence-based guide incorporating the major developments of the last decade: the new diagnostic criteria of the DSM-5, introducing the schizophrenia spectrum and neurodevelopmental disorders, the further evolution of recovery as central to treatment and rehabilitation, advances in understanding the psychopathology of schizophrenia, and the proliferation of psychological and psychosocial modalities for treatment and rehabilitation.