Ebola And Marburg Viruses

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Ebola And Marburg Viruses


Ebola And Marburg Viruses
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Ebola And Marburg Viruses


Ebola And Marburg Viruses
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Author : Patrick Guilfoile
language : en
Publisher:
Release Date : 2020

Ebola And Marburg Viruses written by Patrick Guilfoile and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Diseases categories.


Ebola virus and Marburg virus are related viruses that cause hemorrhagic fevers.

Ebola And Marburg Viruses


Ebola And Marburg Viruses
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Author : Tara C. Smith
language : en
Publisher: Chelsea House Publications
Release Date : 2010

Ebola And Marburg Viruses written by Tara C. Smith and has been published by Chelsea House Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Ebola virus disease categories.


Ebola virus and Marburg virus are related viruses that cause hemorrhagic feversOCoillnesses marked by severe bleeding, organ failure, and, in many cases, death. These viruses are native to Africa, where sporadic outbreaks have occurred for decades. Ebola and Marburg Virus, Second Edition takes a look at the nature and origins of these viruses, transmission, treatment, and current vaccine research.

Ebola And Marburg Viruses


Ebola And Marburg Viruses
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Author : Elena Ryabchikova
language : en
Publisher: Not Applicable
Release Date : 2004

Ebola And Marburg Viruses written by Elena Ryabchikova and has been published by Not Applicable this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.


Electron microscopy has a special place among the wide range of techniques available for viral research. With electron microscopy, a virologist can follow the course of viral infections by visualizing cell damage and viral replication. Each virus family has its own structural and functional attributes, but attention is usually focused on the pathogenic and health-threatening viruses. The Ebola and Marburg filoviruses are notorious among these. The work was done at Vector in Novosibirsk, Russia, by Dr. Ryabchikova. Dr. Price has made it possible for Dr. Ryabchikova to explain her experiments and insights by expanding the descriptions and making the book readable by professionals who are not steeped in the intricacies of virology. In the course of writing this book, Dr. Price has incorporated more complete references of work done by other laboratories so that the story of the filoviruses is a compilation of the research done internationally, but told from the Russian perspective. In Ebola and Marburg Viruses: A View of Infection Using Electron Microscopy, the authors combine recent published and unpublished literature with the insight developed in over 30 years in electron microscopy and 15 years in virology to tell the story of filoviruses and how they invade and conquer their hosts. The book describes the dynamic properties of these viruses, follows the stages of filoviral infection from the individual cell to the whole organism, and reconstructs the sequential events that occur in filoviral infections. The book also demonstrates that, rather than a curiosity, the electron micrograph is an integral tool in studies of viral infection and the pathological process. Ebola and MarburgViruses: A View of Infection Using Electron Microscopy includes over 100 outstanding electron micrographs of filoviruses and the cell and tissue damage they cause during infection. Ebola and Marburg Viruses: A View of Infection Using Electron Microscopy is addressed to investigators in the widely diversified fields of medicine and biology. For this reason, Ryabchikova and Price have carefully elucidated concepts familiar to virologists that may be unfamiliar to nonvirolgists. The book is also designed to provide opportunities for investigators specializing in viruses to correlate their findings with the work of electron microscopists.

Ebola And Marburg Viruses


Ebola And Marburg Viruses
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Author : Hans-Dieter Klenk
language : en
Publisher: Garland Science
Release Date : 2004

Ebola And Marburg Viruses written by Hans-Dieter Klenk and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.


The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Oxford Textbook Of Zoonoses


Oxford Textbook Of Zoonoses
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Author : S.R. Palmer
language : en
Publisher: OUP Oxford
Release Date : 2011-07-14

Oxford Textbook Of Zoonoses written by S.R. Palmer and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-14 with Medical categories.


Divided into three sections along the lines of bacteriology, parasitology and virology, this book comprehensively provides a systematic, cross disciplinary approach to the science and control of all zoonoses, written by international specialists in human and veterinary medicine.

Marburg And Ebolaviruses


Marburg And Ebolaviruses
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Author : Elke Mühlberger
language : en
Publisher: Springer
Release Date : 2017-12-23

Marburg And Ebolaviruses written by Elke Mühlberger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-23 with Medical categories.


This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continents and more than 11,000 deaths. Given the international threat posed by these viruses, the pace and scope of basic research have also greatly intensified, ranging from studies of virus emergence, epidemiology, antiviral countermeasures and human disease to detailed mechanistic studies of virus entry, replication, virion assembly and protein structure. Written by internationally respected experts, this book will appeal to a wide audience and be a valuable resource for basic researchers, clinicians and advanced students alike.

Ebola And Marburg Viruses Replicate In Monocyle Derived Dendritic Cells Without Inducing The Production Of Cytokines And Full Maturation


Ebola And Marburg Viruses Replicate In Monocyle Derived Dendritic Cells Without Inducing The Production Of Cytokines And Full Maturation
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Author :
language : en
Publisher:
Release Date : 2003

Ebola And Marburg Viruses Replicate In Monocyle Derived Dendritic Cells Without Inducing The Production Of Cytokines And Full Maturation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.


Ebola virus (EBOV) and Marburg virus (MARV) cause rapidly progressive hemorrhagic fever with high mortality and may possess specialized mechanisms to evade immune destruction. We postulated that immune evasion could be due to the ability of EBOV and MARV to interfere with dendritic cells (DCs), which link innate and adaptive immune responses. We demonstrate that EBOV and MARV infected and replicated in primary human DCs without inducing cytokine secretion. Infected DC cultures supported exponential viral growth without releasing interferon (IFN)-alpha and were impaired in IFN-alpha production if treated with double-stranded RNA. Moreover, EBOV and MARV impaired the ability of DCs to support T cell proliferation, and infected, immature DCs underwent an anomalous maturation. These findings may explain the profound virulence of EBOV and MARV-DCs are disabled, and an effective early host response is delayed by the necessary reliance on less-efficient secondary mechanisms.